Journal: Journal of Dental Sciences
Article Title: Evaluating thymol vapor for biofilm removal and biocompatibility in curved root canal models in vitro
doi: 10.1016/j.jds.2025.09.001
Figure Lengend Snippet: Early-stage biofilms removal ability of direct thymol treatment in the resin block model. A 48-h bacterial early-stage biofilms model in resin canals was used to assess the antibacterial effects of thymol and CHX through direct contact, vapor treatment, and combination with mechanical instrumentation. Log reductions in CFUs/mL of E. faecalis (A), S. mutans (B), and A. actinomycetemcomitans (C) were determined after direct contact treatment. Log reductions in CFUs/mL of E. faecalis (D), S. mutans (E), and A. actinomycetemcomitans (F) were assessed after vapor-only treatment and vapor combined with mechanical instrumentation. Histograms represent the mean ± standard deviation (SD). The thymol and CHX treatment groups were compared with the untreated control (0 group). ∗ ( P < 0.05), ∗∗( P < 0.01), ∗∗∗ ( P < 0.001), and ∗∗∗∗ ( P < 0.0001), The MI and vapor-thymol cotreatment groups were compare with MI only treatment. a ( P < 0.05), aa ( P < 0.01), and aaaa ( P < 0.0001). One-way ANOVA. The MI and vapor-thymol cotreatment groups were compare with each vapor-thymol dose treatment. # ( P < 0.05), ## ( P < 0.01), ### ( P < 0.001) and #### ( P < 0.0001). Unpair t-test. Abbreviations: THY, thymol; CHX, chlorhexidine; MI, mechanical instrumentation.
Article Snippet: Enterococcus faecalis (BCRC 10789), Streptococcus mutans (ATCC 25175), and Aggregatibacter actinomycetemcomitans (ATCC 33384) were used in this study.
Techniques: Blocking Assay, Standard Deviation, Control